A Dual Protective Drug Delivery System Based on Lipid Coated Core-Shell Mesoporous Silica for Efficient Delivery of Cabazitaxel to Prostate Cancer Cells
- Creator: Mohanan, Shan , Sathish, C. I. , Adams, Thomas J. , Kan, Stanislav , Liang, Mingtao , Vinu, Ajayan
- Resource Type: journal article
- Date: 2023
Blockade of ROS production inhibits oncogenic signaling in acute myeloid leukemia and amplifies response to precision therapies
- Creator: Germon, Zacary P. , Sillar, Jonathan R. , McLachlan, Tabitha , Schjenken, John E. , Skerrett-Byrne, David A. , Huang, Honggang , Melo-Braga, Marcella N. , Plank, Maximillan W. , Alvaro, Frank , Chamberlain, Janis , De Iuliis, Geoff , Aitken, R. John , Mannan, Abdul , Nixon, Brett , Wei, AH , Enjeti, Anoop K. , Huang, Y , Lock, RB , Larsen, MR , Lee, Heather , Vaghjiani, V , Cain, JE , de Bock, CE , Duchatel, Ryan J. , Verrills, Nicole M. , Dun, Matthew D. , Staudt, Dilana , Murray, Heather C. , Findlay, Izac J. , Jackson, Evangeline R. , McEwen, Holly P. , Douglas, Alicia M.
- Resource Type: journal article
- Date: 2023
The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location
- Creator: Liu, Ilon , Jiang, Li , Mire, Hafsa M. , Madlener, Sibylle , Mayr, Lisa , Quezada, Michael A. , Trissal, Maria , Panditharatna, Eshini , Ernst, Kati J. , Vogelzang, Jayne , Gatesman, Taylor A. , Halbert, Matthew E. , Samuelsson, Erik R. , Palova, Hana , Pokorna, P , Sterba, J , Slaby, O , Geyeregger, R , Diaz, A , Findlay, Izac J. , Dun, Matthew D. , Resnick, A , Suvà, ML , Marco Salas, Sergio , Jones, DTW , Agnihotri, S , Svedlund, J , Koschmann, C , Haberler, C , Czech, T , Slavc, I , Cotter, JA , Ligon, KL , Alexandrescu, S , Beck, Alexander , Yung, WKA , Arrillaga-Romany, I , Gojo, J , Monje, M , Nilsson, M , Filbin, MG , Hack, Olivia A. , Jeong, Daeun , Shaw, McKenzie L. , Englinger, Bernhard , LaBelle, Jenna
- Resource Type: journal article
- Date: 2022
LncRNA GIRGL drives CAPRIN1-mediated phase separation to suppress glutaminase-1 translation under glutamine deprivation
- Creator: Wang, Ruijie , Cao, Leixi , Thorne, Rick Francis , Zhang, Xu Dong , Li, Jinming , Shao, Fengmin , Zhang, Lirong , Wu, Mian
- Resource Type: journal article
- Date: 2021
Warburg effect targeting Co(III) cytotoxin chaperone complexes
- Creator: Glenister, Alexandra , Chen, Catherine K. J. , Paterson, David J. , Renfrew, Anna K. , Simone, Michela I. , Hambley, Trevor W.
- Resource Type: journal article
- Date: 2021
c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesis
- Creator: Feng, Yu Chen , Liu, Xiao Ying , Teng, Liu , Ji, Qiang , Wu, Yongyan , Li, Jin Ming , Gao, Wei , Zhang, Yuan Yuan , La, Ting , Tabatabaee, Hessam , Yan, Xu Guang , Jamaluddin, M. Fairuz B. , Zhang, Didi , Guo, Su Tang , Scott, Rodney J. , Liu, Tao , Thorne, Rick F. , Zhang, Xu Dong , Jin, Lei
- Resource Type: journal article
- Date: 2020
ProNGF/NGF, their receptors and nerves in human cancers
- Creator: Gao, Fangfang
- Resource Type: thesis
- Date: 2020
A Warburg effect targeting vector designed to increase the uptake of compounds by cancer cells demonstrates glucose and hypoxia dependent uptake
- Creator: Glenister, Alexandra , Simone, Michela I. , Hambley, Trevor W.
- Resource Type: journal article
- Date: 2019
A p53-responsive miRNA network promotes cancer cell quiescence
- Creator: La, Ting , Liu, Guang Zhi , Guo, Su Tang , Liu, Tao , Thorne, Rick F. , Jin, Lei , Zhang, Xu Dong , Farrelly, Margaret , Cole, Nicole , Feng, Yu Chen , Zhang, Yuan Yuan , Sherwin, Simonne K. , Yari, Hamed , Tabatabaee, Hessam , Yan, Xu Guang
- Resource Type: journal article
- Date: 2018
Cooperativity of HOXA5 and STAT3 is critical for HDAC8 inhibition-mediated transcriptional Activation of PD-L1 in human melanoma cells
- Creator: Wang, Yu Fang , Liu, Fen , Sherwin, Simonne , Farrelly, Margaret , Yan, Xu Guang , Croft, Amanda , Liu, Tao , Jin, Lei , Zhang, Xu Dong , Jiang, Chen Chen
- Resource Type: journal article
- Date: 2018
Inhibition of HSP90 by AUY922 preferentially kills mutant KRAS colon cancer cells by activating Bim through ER stress
- Creator: Wang, Chun Yan , Guo, Su Tang , Wang, Jia Yu , Liu, Fen , Zhang, Yuan Yuan , Yari, Hamed , Yan, Xu Guang , Jin, Lei , Zhang, Xu Dong , Jiang, Chen Chen
- Resource Type: journal article
- Date: 2016
Quinolone-1-(2H)-ones as hedgehog signalling pathway inhibitors
- Creator: Trinh, Trieu N. , McLaughlin, Eileen A. , Abdel-Hamid, Mohammed K. , Gordon, Christopher P. , Bernstein, Ilana R. , Pye, Victoria , Cossar, Peter , Sakoff, Jennette A. , McCluskey, Adam
- Resource Type: journal article
- Date: 2016
Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922
- Creator: Wang, Chun Yan , Guo, Su Tang , Jin, Lei , Zhang, Xu Dong , Jiang, Chen Chen , Wang, Jia Yu , Yan, Xu Guang , Farrelly, Margaret , Zhang, Yuan Yuan , Liu, Fen , Yari, Hamed , La, Ting , Lei, Fu Xi
- Resource Type: journal article
- Date: 2016
PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity
- Creator: Gilan, O. , Diesch, J. , Dhillon, A. S. , Amalia, M. , Jastrzebski, K. , Chueh, A. C. , Verrills, N. M. , Pearson, R. B. , Mariadason, J. M. , Tulchinsky, E. , Hannan, R. D.
- Resource Type: journal article
- Date: 2015
CAVATAK (Coxsackievirus A21) displays potent oncolytic activity in BRAFV600E mutant melanoma cells resistant to selective BRAF kinase inhibitors
- Creator: Shafren, D. R. , Farrelly, M. , Croft, A. J. , Davies, B. , Stewart, J. , Ingham, R. , Quah, M. Y. , Au, G. , Hersey, P.
- Resource Type: conference paper
- Date: 2011
Apoptosis and melanoma: how new insights are effecting the development of new therapies for melanoma
- Creator: Hersey, Peter
- Resource Type: journal article
- Date: 2006
Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate
- Creator: Sohn, Kyoung-Jin , Croxford, Ruth , Yates, Zoe , Lucock, Mark , Kim, Young-In
- Resource Type: journal article
- Date: 2004